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Cystic fibrosis: questions on the new drug Vertex

Published: 23 July 2014
What:ÌýInvestors and patients were exuberant when Vertex Pharmaceuticals released results from clinical trials showing that cystic fibrosis (CF) patients’ lung function improved on an experimental two-drug regimen. But Ìýtwo independent teams of scientists, one from º£ÍâÖ±²¥bÕ¾, published studies showing that the medications interfere with each other, at least when they are administered to human cells in a laboratory dish.

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The studies published in the journalÌýScience Translational MedicineÌýraise fundamental questions about how the drugs work in CF patients and also suggest that a different strategy might be more effective.

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Expertise:Ìýº£ÍâÖ±²¥bÕ¾ prof. Gergely Lukacs, Faculty of Medicine (Physiology), Canada Research Chair in Cystic Fibrosis

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Source:Ìý

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